![]() ![]() The shaking motion helps to overcome mass transfer limitations, ensuring uniform distribution of nutrients and oxygen throughout the cell culture. Incubator shakers aid in optimizing protein expression by providing a controlled environment that facilitates the translation of mRNA into proteins. Once mRNA molecules are successfully transfected into cells, the next step is to ensure efficient protein expression. This improved transfection efficiency translates into higher yields of mRNA-transfected cells, which are essential for subsequent stages of vaccine development and testing. The shaking motion creates gentle agitation, helping to improve the contact between mRNA molecules and cell membranes, thereby facilitating higher uptake rates. Incubator shakers play a crucial role in improving transfection efficiency by enhancing the delivery of mRNA molecules into cells. Transfection, the process of introducing mRNA molecules into cells, is a vital step in mRNA vaccine development. This level of control not only enhances the yield and purity of mRNA but also reduces the likelihood of experimental variability, increasing the reliability of results. They maintain precise temperature, humidity and agitation levels, allowing cells to thrive and efficiently carry out the protein synthesis process. Incubation shakers are specialized instruments designed to create optimal growth conditions and controlled environments for cultures ensuring that mRNA molecules are efficiently translated into proteins. The research and development of mRNA technologies rely heavily on the use of advanced laboratory equipment, with incubation shakers playing a crucial role as the “universal workhorse” of mRNA-based therapy development. To facilitate the development and production of mRNA vaccines, it is essential to have advanced laboratory equipment that meets the stringent requirements of this specialized field.Īddressing the Unique Challenges of mRNA Vaccine Development ![]() After the battle against the pandemic, the field of cancer therapies is now in the focus of research, where mRNA is a very promising approach. This method has proven immensely successful in the development of COVID-19 vaccines, enabling rapid response and deployment. Once inside our cells, this mRNA is translated into the viral protein, triggering an immune response without causing the actual infection. However, mRNA vaccines take a different approach by delivering a small piece of synthetic mRNA that encodes a viral protein. Traditional vaccines often involve introducing weakened or inactivated pathogens to stimulate an immune response. At your request, we can provide photos of the equipment in your order after it has been tested and cleaned.At the heart of mRNA technology lies the ability to develop vaccines and therapeutics that work in harmony with our own immune systems. We often have multiple units of each model in stock and sometimes we're unable to feature photos of every single unit. Please bear in mind that the equipment shown is currently in storage in our warehouse and that in addition to testing each machine we will clean all the equipment thoroughly prior to shipment. If you have particular testing requirements or requests please let us know and we’ll work with you to make sure these requirements are addressed during testing. ![]() While we can’t test for a specific analytical application, we will do our best to simulate the conditions under which the equipment will be run. Our technicians test all equipment to confirm that it operates properly and to the manufacturer’s specifications. ![]() We test the shaking mechanism and run the units for an extended period of time to make sure all set points and parameters operate on continuous setting. We replace any hardware or parts as is necessary and clean all incubators thoroughly prior to shipment. Our technicians test incubators using a calibrated digital chart recorder to verify the accuracy of temperature controls and readouts. This set up is ideal for labs in which multiple users need to utilize the same incubator simultaneously for multiple applications.Ĭlick Here to see the Infors HT Multitron on the American Instrument Exchange YouTube channel.Īll of our equipment is used and reconditioned. This Infors AG Multitron incubator shaker is a two chamber stack with two separate, independently controlled chambers that are each large enough to accommodate 5L Erlenmeyer flasks. Infors HT Multitron incubator shaker stack ![]()
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